Correction to: Circulating Growth Differentiation Factor 11/8 Levels Decline With Age.
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چکیده
In the article by Poggioli et al, “Circulating Growth Differentiation Factor 11/8 Levels Decline with Age,” which published in the January 8, 2016 issue of the journal (Circ Res. 2016;118:29–37. DOI: 10.1161/CIRCRESAHA.115.307521), corrections were needed to the Online Supplement. In Online Table I, we reported values that demonstrate an effect of GDF11/8 on heart weight and body mass. Since then, we have discovered multiple errors present in Online Table I, primarily from spreadsheet errors by one trainee. Specifically, the “Body weight values for Day 0 and 9” for old saline and old GDF11 (0.5mg), Delta body weight Day 0–9 (%) for old saline and HW/BW ratio for old GDF11 (0.5 mg) that we presented in Online Table I in that article, did not reflect the raw data that we originally collected. In this corrigendum, we present the data that we intended to report in Poggioli et al, and explain how the errors occurred. We have also included two columns providing additional data of tibia length and heart weight to tibia length ratio, to show the tibia versus body weight normalization. The errors below occurred in the Lee Laboratory.
منابع مشابه
Circulating Growth Differentiation Factor 11/8 Levels Decline With Age.
RATIONALE Growth differentiation factor 11 (GDF11) and GDF8 are members of the transforming growth factor-β superfamily sharing 89% protein sequence homology. We have previously shown that circulating GDF11 levels decrease with age in mice. However, a recent study by Egerman et al reported that GDF11/8 levels increase with age in mouse serum. OBJECTIVE Here, we clarify the direction of change...
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عنوان ژورنال:
- Circulation research
دوره 122 1 شماره
صفحات -
تاریخ انتشار 2018